NSW Chief Health Officer Dr Kerry Chant called on people from Penrith and who enter Penrith for work or shopping to be vigilant after 12 new cases were identified in the region overnight.
She said the virus "has the potential to creep", adding that residents should not enter the area to shop unless they had to.
NSW recorded 199 new locally acquired cases of COVID-19 in the 24 hours to 8pm Monday night. Of these, the source of infection for 111 cases is under investigation.
Fifty cases were infectious in the community, and the isolation status of 47 cases remains under investigation.
Premier Gladys Berejiklian said NSW was aiming for six million vaccine shots by the end of August.
Cases in the Penrith Local Government Area (LGA) are now at 40, with 19 of these from an unknown source.
The Hawkesbury remains at 6, and the Blue Mountains remains at three.
Blacktown now has 220 cases and 79 of these are from an unknown source.
There are now 23 cases in The Hills Shire.
The latest venue of concern for Penrith announced by NSW Health was Officeworks Penrith, 273 High Street, on Monday, July 26, 12pm - 5pm.
Anyone who attended at this time is a "close contact" and must immediately get tested and self-isolate for 14 days regardless of the result. If close contacts have not been contacted by NSW Health by SMS or phone call, they must call 1800 943 553.
For a full list of venue alerts, which is updated daily, go to https://www.health.nsw.gov.au/Infectious/covid-19/Pages/case-locations-and-alerts.aspx
Testing locations are available on the NSW Health website. Local locations can also be found at Wentworth Healthcare's website.
There are also GP-led testing clinics (please check the NSW Health website and contact the GP clinic before attending):
- Windsor: GP Respiratory Clinic, 2 Kable St, Windsor (previously located at 6 Kable St, Windsor). Mon - Thurs 1.30 - 5.30.
- Richmond: Laverty Pathology Drive-through, Hawkesbury Family Practice, Rear Carpark, 86 Lennox Street, Richmond. Mon-Fri.
- Vineyard: 4Cyte Pathology Drive-through & Walk-In Clinic, 357 Windsor Road, Vineyard. Mon- Fri.
- Windsor: ACL Drive-through, Hawkesbury District Health Service, 2 Day St Windsor. Mon- Fri.