Postponed by a year, the biggest sporting event since the coronavirus brought the world to a halt will commence at the Stadio Olimpico in Rome - a milestone both for European and world sports.
The opening match of soccer's European Championship on Friday evening will be played in the capital of Italy, the first country outside Asia to get struck by the pandemic and the first in the world to implement a nationwide lockdown.
The tournament represents a major step forward on the path toward recovery after one of the darkest chapters in the continent's history since World War II. More than 1 million Europeans have died in the pandemic, including almost 127,000 Italians.
"After everything that's happened, now the situation is improving, I think the time has come to start providing fans with something to be satisfied about," said Italy coach Roberto Mancini, who tested positive for COVID-19 in November but was asymptomatic.
The tournament was postponed when countries were scrambling to contain virus outbreaks and major sporting events around the world were cancelled or put on hold.
Many worry that it's still not safe to bring tens of thousands of fans together in stadiums across Europe, but organisers hope measures including crowd limitations, staggered arrival times for fans, social distancing rules and lots of hand sanitiser will help prevent a resurgence of virus infections, which have dropped sharply in Europe in recent months.
In Rome, fans entering the stadium are required to bring documentation showing they have been vaccinated against the virus, tested negative in the 48 hours before the match or already had the disease.
The sporting world is watching.
If everything goes smoothly, Euro 2020 can give a confidence boost for other major sporting events, like the Tokyo Olympics, scheduled to commence on July 23 - also a year late.
If it doesn't, it would be a serious setback that could have ramifications beyond soccer.
The virus already has had an impact on the tournament, which for the first time is not being hosted by one or two nations but is spread across the continent with matches in 11 cities.
Captain Sergio Busquets is among two Spain players to teste positive for COVID-19 in the lead-up, as did two of Sweden's players.
The Spanish squad was getting vaccinated Friday.
Russia winger Andrey Mostovoy then became the first player to be cut from a national team on Friday after testing positive.
Italy's opening match against Turkey will bring together about 16,0000 fans - the biggest crowd in the country since it went into a full lockdown 15 months ago - even though the stadium will be at 25 per cent of its capacity.
In Rome and elsewhere in Italy, most virus restrictions have been lifted.
A midnight curfew and a requirement to wear a mask outside one's home are the most tangible ways in which the pandemic still affects the daily lives of citizens.
Australian Associated Press