$3 million worth of cannabis was found at a Schofields property on Sunday, July 27.
Detectives from the State Crime Command's Drug Squad stopped three cars on Sunday afternoon as they drove along Meadows Road.
After speaking to the three men driving the cars, they executed a search warrant for a nearby property.
When Detectives arrived at the property they located a large indoor hydroponic cannabis plantation - containing more than 600 plants and around 10KG of cannabis which had been harvested.
Detectives estimated that the potential street value of the cannabis seized is in excess of $3 million.
The three men who had earlier been stopped by police, were arrested and taken to Quakers Hill Police Station where they were each charged with cultivate large commercial quantity of cannabis.
Two of the men – a 62-year-old from Quakers Hill and a 52-year-old from Merrylands – were refused bail and appeared in Blacktown Local Court on Monday where they were refused bail.
They will appear in Penrith Local Court on September 26.
The third man – a 67-year-old from Merrylands – was granted conditional bail and will appear at Blacktown Local Court on August 19.
The site of the plantation has been dismantled by police and numerous items of equipment, allegedly used in the cultivation of cannabis, have been seized for evidentiary purposes.